With its mix of open fields, mature forests and wetlands, Murphys Point offers a diversity of wildlife viewable from park trails. Deer are very common, especially in the campground. A paddle on the lakes and rivers often reveals beaver, otters, loons and other waterfowl. In winter, the hustle and bustle of wildlife is evident on ski trails criss-crossed by tracks of mink, fisher, coyote, deer, otter and porcupine.

The park is home to five species of turtles, eight species of frogs and toads and eight species of snakes, including Canada's largest, the black rat snake.

Murphys Point also provides excellent birding opportunities. During the spring and early summer especially, the lush green of new forest growth is punctuated by the bold feathers of scarlet tanagers, indigo buntings, yellow warblers and Baltimore orioles, not to mention colourful wildflowers.